Dr. Stein is the Chief of Leukemia Service in the Division of Hematologic Malignancies, associate attending physician, clinical investigator and Director of the Program for Drug Development in Leukemia at MSK. He conducts novel Phase 1 clinical trials of compounds that target the genetic and epigenetic basis of myeloid malignancies and serves as the lead investigator at MSK for the BEAT AML master clinical trial. Dr. Stein led the clinical trials of IDHIFA® and TIBSOVO®, isocitrate dehydrogenase (IDH) inhibitors, in patients with relapsed and refractory AML that led to their FDA approvals.