A differentiated
Approach to Cure Cancer

What we do

Differentiation Therapy: Transforming the way we treat cancer

Progress in any field is often non-linear and inflection points of exponential growth are fueled by breakthroughs in scientific understanding. How developmental biology programs are coopted by cancer cells to enable rapid proliferation of poorly differentiated cells is one such breakthrough. Our increased understanding of the developmental pathways perturbed in cancer is based on the integration of information-rich, multi-omics datasets that illuminate the key drivers of this disease. These recent advances allow us to radically re-focus the mechanism of our cancer therapeutics from cell killing to transformation of tumor cells into more normal-functioning, mature (benign) cells. This paradigm shift to differentiation-based therapies offers life-saving, transformative medicines for patients.

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Transforming cells
Transforming lives
How we do it

AURigin: A Multi-Omics Platform for a systems-level understanding of differentiation

At Auron, we have built a proprietary, machine learning based platform called AURigin that integrates large, multi-omic datasets derived from primary human tissue samples. Using the platform, we have constructed a systems-biology level understanding of normal tissue differentiation and tumor development. Custom applications within AURigin enable direct access to high quality, multi-dimensional datasets used by Auron’s scientists to identify key therapeutic targets in well-defined patient populations. Rapid development of novel therapies is facilitated by targeted clinical trial designs and accelerates the approval of new cancer treatments for patients.

Our approach
Who we are

The Auron Team: Changing the way we think about cancer, Changing Lives

By viewing cancer through a developmental biology lens, we are shifting the way we think about new cancer therapies. We have assembled a world class team of differentiation biology experts, drug hunters, computational biologists, and physician scientists all united in a common goal: bringing effective differentiation-based therapies to cancer patients. At Auron, we believe that changing the way we think about cancer can change lives.

About us